Cell Signaling Epcam (Vu1d9) Mouse mAb (Alexa Fluor<LT/>Sup&Gt;®<LT/>/Sup&Gt; 488 Conjugate)

Name: Cell Signaling Epcam (Vu1d9) Mouse mAb (Alexa Fluor Sup&Gt;® /Sup&Gt; 488 Conjugate)
SKU: CSSPQ-5198S
Price: 465.00 USD

List Price $465.00 Your Price $465.00

Cell Signaling Epcam (Vu1d9) Mouse mAb (Alexa FluorSup≫®/Sup≫ 488 Conjugate) - CSSPQ (Additional S&H or Hazmat Fees May Apply)

NETA PART: CSSPQ-5198S

MFG.PART: 5198S

UNSPSC: 12352203

Manufacturer: Cell Signaling

Description

Size	100 µl (50 tests)
Reactivity	H
Sensitivity	Endogenous
Source/Isotype	Mouse IgG1
Application/Dilution	{Immunofluorescence (Immunocytochemistry): 1:200 - 1:400, Flow Cytometry (Fixed/Permeabilized): 1:50 - 1:200, Flow Cytometry (Live): 1:50 - 1:200}
Storage	Supplied in PBS (pH 7.2), less than 0.1% sodium azide and 2 mg/mL BSA. Store at 4°C. Do not aliquot the antibody. Protect from light. Do not freeze.
Specificity/Sensitivity	EpCAM (VU1D9) Mouse mAb (Alexa Fluor® 488 Conjugate) detects endogenous levels of total EpCAM protein.
Species Reactivity	Human
Source/Purification	Monoclonal antibody is produced by immunizing animals with NCI-H69 small cell lung carcinoma cells.
Background	Epithelial cell adhesion and activating molecule (EpCAM/CD326) is a transmembrane glycoprotein that mediates Ca2+-independent, homophilic adhesions on the basolateral surface of most epithelial cells. EpCAM is not expressed in adult squamous epithelium, but it is highly expressed in adeno and squamous cell carcinomas (1). Research studies identified EpCAM as one of the first tumor-associated antigens, and it has long been a marker of epithelial and tumor tissue. Investigators have shown that EpCAM is highly expressed in cancer cells (reviewed in 2,3).

Specifications