Cell Signaling Hpc4-Tag Antibody

Name: Cell Signaling Hpc4-Tag Antibody
SKU: CSSPQ-68083S
Price: 317.00 USD

List Price $317.00 Your Price $317.00

Cell Signaling Hpc4-Tag Antibody - CSSPQ (Additional S&H or Hazmat Fees May Apply)

NETA PART: CSSPQ-68083S

MFG.PART: 68083S

UNSPSC: 41120000

Manufacturer: Cell Signaling

Size	100 µl
Reactivity	All
Sensitivity	Transfected Only
Source/Isotype	Rabbit
Application/Dilution	{Western Blotting: 1:1000, Immunoprecipitation: 1:50}
Storage	Supplied in 10 mm sodium HEPES (pH 7.5), 150 mm NaCl, 100 µg/mL BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
Specificity/Sensitivity	HPC4-Tag Antibody recognizes recombinant proteins containing the HPC4-tag. This antibody recognizes the HPC4-tag fused to either the amino or carboxy terminus of targeted proteins in transfected cells.
Species Reactivity	All Species Expected
Source/Purification	Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues of the HPC4-tag.
Background	Epitope tags are useful for the labeling and detection of proteins using immunoblotting, immunoprecipitation, and immunostaining techniques. Because of their small size, they are unlikely to affect the tagged protein’s biochemical properties.HPC4-tag is a 12 amino acid sequence derived from protein C, which is a vitamin K-dependent plasma zymogen. Protein C is activated by proteolytic cleavage of the thrombin-thrombomodulin complex to form an anticoagulant enzyme (1,2). This peptide can be expressed and detected with the protein of interest as an amino-terminal or carboxy-terminal fusion (3,4).