Cell Signaling Prk2 (D10a10) Rabbit mAb

Name: Cell Signaling Prk2 (D10a10) Rabbit mAb
SKU: CSSPQ-8697S
Price: 351.00 USD

List Price $351.00 Your Price $351.00

Cell Signaling Prk2 (D10a10) Rabbit mAb - CSSPQ (Additional S&H or Hazmat Fees May Apply)

NETA PART: CSSPQ-8697S

MFG.PART: 8697S

UNSPSC: 12352203

Manufacturer: Cell Signaling

Size	100 µl
Reactivity	H Mk B Pg
Sensitivity	Endogenous
Molecular Weight (kDa)	140
Source/Isotype	Rabbit IgG
Application/Dilution	{Western Blotting: 1:1000, Immunoprecipitation: 1:50}
Storage	Supplied in 10 mm sodium HEPES (pH 7.5), 150 mm NaCl, 100 µg/mL BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
Specificity/Sensitivity	PRK2 (D10A10) Rabbit mAb recognizes endogenous levels of total PRK2 protein. This antibody does not cross-react with PRK1.
Species Reactivity	Human, Monkey, Bovine, Pig
Source/Purification	Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Leu633 of human PRK2 protein.
Background	The protein kinase C-related kinases (PRKs) are a subfamily of Ser/Thr-specific kinases with a catalytic domain highly homologous to the PKC family (1-3). They are effectors of Rho family GTPases (4-6) and are activated by fatty acids and phospholipids in vitro (7,8). Activation in vitro and in vivo involves the activation loop phosphorylation of PRK1 (Thr774)/PRK2 (Thr816) by PDK1 (9,10).