Cell Signaling Calbindin (D1i4q) Xp Rabbit mAb (Alexa Fluor 594 Conjugate)

Name: Cell Signaling Calbindin (D1i4q) Xp Rabbit mAb (Alexa Fluor 594 Conjugate)
SKU: CSSPQ-88831S
Price: 465.00 USD

List Price $465.00 Your Price $465.00

Cell Signaling Calbindin (D1i4q) Xp Rabbit mAb (Alexa Fluor 594 Conjugate) - CSSPQ (Additional S&H or Hazmat Fees May Apply)

NETA PART: CSSPQ-88831S

MFG.PART: 88831S

UNSPSC: 12352203

Manufacturer: Cell Signaling

Description

Size	100 µl (50 tests)
Reactivity	H M R
Sensitivity	Endogenous
Source/Isotype	Rabbit IgG
Application/Dilution	{Immunofluorescence (Frozen): 1:50}
Storage	Supplied in PBS (pH 7.2), less than 0.1% sodium azide and 2 mg/mL BSA. Store at 4°C. Do not aliquot the antibody. Protect from light. Do not freeze.
Specificity/Sensitivity	Calbindin (D1I4Q) XP® Rabbit mAb (Alexa Fluor® 594 Conjugate) recognizes endogenous levels of total calbindin protein.
Species Reactivity	Human, Mouse, Rat
Source/Purification	Monoclonal antibody is produced by immunizing animals with recombinant protein specific to the amino terminus of human calbindin protein.
Background	Calcium-binding proteins of different subfamilies regulate the second messenger calcium. Calbindin, calmodulin, S-100, parvalbumin, and troponin C are members of the low molecular weight calcium-binding protein family (1). Calbindin is expressed in discrete neuronal populations within the CNS and is thought to act as an intracellular calcium buffering protein. Most Purkinje cells express calbindin, which is expressed when neurons start to migrate and differentiate. In contrast, other calcium buffering proteins, such as parvalbumin, are expressed later during development and in parallel with increasing neuronal activity (2).

Specifications