Cell Signaling Androgen Receptor (D6f11) Xp® Rabbit mAb (BSA And Azide Free)

Name: Cell Signaling Androgen Receptor (D6f11) Xp® Rabbit mAb (BSA And Azide Free)
SKU: CSSPQ-23791SF
Price: 865.00 USD

List Price $865.00 Your Price $865.00

Cell Signaling Androgen Receptor (D6f11) Xp® Rabbit mAb (BSA And Azide Free) - CSSPQ (Additional S&H or Hazmat Fees May Apply)

NETA PART: CSSPQ-23791SF

MFG.PART: 23791SF

UNSPSC: 12352203

Manufacturer: Cell Signaling

Size	100 µg
Reactivity	H
Sensitivity	Endogenous
Molecular Weight (kDa)	110
Source/Isotype	Rabbit IgG
Application/Dilution	{}
Storage	Supplied in 1X PBS, BSA and Azide Free.For standard formulation of this product see product #5153.
Specificity/Sensitivity	Androgen Receptor (D6F11) XP® Rabbit mAb (BSA and Azide Free) detects endogenous levels of total androgen receptor protein.
Species Reactivity	Human
Source/Purification	Monoclonal antibody is produced by immunizing animals with recombinant protein corresponding to residues near the amino terminal region of human androgen receptor protein.
Background	Androgen receptor (AR), a zinc finger transcription factor belonging to the nuclear receptor superfamily, is activated by phosphorylation and dimerization upon ligand binding (1). This promotes nuclear localization and binding of AR to androgen response elements in androgen target genes. Research studies have shown that AR plays a crucial role in several stages of male development and the progression of prostate cancer (2,3).