Cell Signaling Pcna (D3h8p) Xp® Rabbit mAb (BSA And Azide Free)

Name: Cell Signaling Pcna (D3h8p) Xp® Rabbit mAb (BSA And Azide Free)
SKU: CSSPQ-71395SF
Price: 865.00 USD

List Price $865.00 Your Price $865.00

Cell Signaling Pcna (D3h8p) Xp® Rabbit mAb (BSA And Azide Free) - CSSPQ (Additional S&H or Hazmat Fees May Apply)

NETA PART: CSSPQ-71395SF

MFG.PART: 71395SF

UNSPSC: 12352203

Manufacturer: Cell Signaling

Size	100 µg
Reactivity	H M R Mk
Sensitivity	Endogenous
Molecular Weight (kDa)	36
Source/Isotype	Rabbit IgG
Application/Dilution	{}
Storage	Supplied in 1X PBS, BSA and Azide Free.For standard formulation of this product see product #13110.
Specificity/Sensitivity	PCNA (D3H8P) XP® Rabbit mAb (BSA and Azide Free) recognizes endogenous levels of total PCNA protein.
Species Reactivity	Human, Mouse, Rat, Monkey
Source/Purification	Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human PCNA protein.
Background	Proliferating cell nuclear antigen (PCNA) is a member of the DNA sliding clamp family of proteins that assist in DNA replication (1). Crystal structure data suggests that a PCNA homotrimer ring can encircle and slide along the DNA double helix (2). Multiple proteins involved in DNA replication, DNA repair, and cell cycle control bind to PCNA rather than directly associating with DNA, thus facilitating fast processing of DNA (reviewed in 3). PCNA protein expression is a well-accepted marker of proliferation.