Cell Signaling Znf185 (E6w4i) Rabbit mAb

Name: Cell Signaling Znf185 (E6w4i) Rabbit mAb
SKU: CSSPQ-37430S
Price: 351.00 USD

List Price $351.00 Your Price $351.00

Cell Signaling Znf185 (E6w4i) Rabbit mAb - CSSPQ (Additional S&H or Hazmat Fees May Apply)

NETA PART: CSSPQ-37430S

MFG.PART: 37430S

UNSPSC: 12352203

Manufacturer: Cell Signaling

Size	100 µl
Reactivity	H
Sensitivity	Endogenous
Molecular Weight (kDa)	85
Source/Isotype	Rabbit IgG
Application/Dilution	{Western Blotting: 1:1000, Immunoprecipitation: 1:200, Immunohistochemistry (Paraffin): 1:50 - 1:200, Immunofluorescence (Immunocytochemistry): 1:100 - 1:400}
Storage	Supplied in 10 mm sodium HEPES (pH 7.5), 150 mm NaCl, 100 µg/mL BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
Specificity/Sensitivity	ZNF185 (E6W4I) Rabbit mAb recognizes endogenous levels of total ZNF185 protein.
Species Reactivity	Human
Source/Purification	Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Gly50 of human ZNF185 protein.
Background	Zinc finger protein 185 (ZNF185) is an actin cytoskeleton-associated protein that regulates anchorage dependent growth of prostate cancer cells (1). ZNF185 expression is regulated by p63 and p53 (2,3). ZNF185 localization and expression was found to have prognostic value in epithelial cancer and pancreatic ductal carcinoma (2,4), and its overexpression reduces proliferation and invasion of lung adenocarcinoma cells (5).