Cell Signaling Cd43 (Mt1) Mouse mAb

Name: Cell Signaling Cd43 (Mt1) Mouse mAb
SKU: CSSPQ-38428S
Price: 364.00 USD

List Price $364.00 Your Price $364.00

Cell Signaling Cd43 (Mt1) Mouse mAb - CSSPQ (Additional S&H or Hazmat Fees May Apply)

NETA PART: CSSPQ-38428S

MFG.PART: 38428S

UNSPSC: 12352203

Manufacturer: Cell Signaling

Size	100 µl
Reactivity	H
Source/Isotype	Mouse IgG1
Application/Dilution	{IHC Leica Bond: 1:50 - 1:200, Immunohistochemistry (Paraffin): 1:50}
Storage	Supplied as liquid tissue culture supernatant containing sodium azide as a preservative. Stable for 6 months when stored at 4°C. Do not aliquot the antibody.
Specificity/Sensitivity	CD43 (MT1) Mouse mAb recognizes endogenous levels of CD43 protein.
Species Reactivity	Human
Source/Purification	Monoclonal antibody is produced by immunizing animals with human lymphocytes.
Background	CD43, also known as leukosialin and sialophorin, is a type I transmembrane sialylated, negatively charged mucin that is expressed on the surface of most hematopoietic cells (1,2). CD43 plays an important role in T lymphocyte function by negatively regulating antigen-specific T cell activation and interfering with cellular adhesion and proliferation (2,3). It also has been reported that CD43 is involved in viral clearance (3). Aberrant expression of CD43 is associated with several diseases, such as Wiskott-Aldrich syndrome and acute leukemia (3,4).