Cell Signaling Psa/Klk3 (D11e1) Xp ® Rabbit mAb (BSA And Azide Free)

Name: Cell Signaling Psa/Klk3 (D11e1) Xp ® Rabbit mAb (BSA And Azide Free)
SKU: CSSPQ-36476SF
Price: 865.00 USD

List Price $865.00 Your Price $865.00

Cell Signaling Psa/Klk3 (D11e1) Xp ® Rabbit mAb (BSA And Azide Free) - CSSPQ (Additional S&H or Hazmat Fees May Apply)

NETA PART: CSSPQ-36476SF

MFG.PART: 36476SF

UNSPSC: 12352203

Manufacturer: Cell Signaling

Size	100 µg
Reactivity	H
Sensitivity	Endogenous
Molecular Weight (kDa)	29
Source/Isotype	Rabbit IgG
Application/Dilution	{}
Storage	Supplied in 1X PBS, BSA and Azide Free.For standard formulation of this product see product #2475
Specificity/Sensitivity	PSA/KLK3 (D11E1) XP® Rabbit mAb (BSA and Azide Free) recognizes endogenous levels of total PSA/KLK3 protein.
Species Reactivity	Human
Source/Purification	Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Val72 of human PSA/KLK3 protein.
Background	Kallikrein 3 (KLK3), also known as Prostate Specific Antigen (PSA), is a member of the glandular kallikrein subfamily of serine proteases (1). It is produced by prostate epithelial cells and is secreted into prostatic ducts. Upon cleavage of 7 amino-terminal amino acids (2), it is activated to liquefy semen in the seminal coagulum. Although PSA/KLK3 is produced in healthy individuals, investigators have found abnormally high levels in the blood of men with advanced prostate cancer (2,3).