Cell Signaling Psd95 (D74d3) Xp ® Rabbit mAb (BSA And Azide Free)

Name: Cell Signaling Psd95 (D74d3) Xp ® Rabbit mAb (BSA And Azide Free)
SKU: CSSPQ-60642SF
Price: 865.00 USD

List Price $865.00 Your Price $865.00

Cell Signaling Psd95 (D74d3) Xp ® Rabbit mAb (BSA And Azide Free) - CSSPQ (Additional S&H or Hazmat Fees May Apply)

NETA PART: CSSPQ-60642SF

MFG.PART: 60642SF

UNSPSC: 12352203

Manufacturer: Cell Signaling

Description

Size	100 µg
Reactivity	H M R
Sensitivity	Endogenous
Molecular Weight (kDa)	95
Source/Isotype	Rabbit IgG
Application/Dilution	{}
Storage	Supplied in 1X PBS, BSA and Azide Free.For standard formulation of this product see product #3409
Specificity/Sensitivity	PSD95 (D74D3) XP® Rabbit mAb (BSA and Azide Free) detects endogenous levels of total PSD95 protein.
Species Reactivity	Human, Mouse, Rat
Source/Purification	Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues in the amino-terminal sequence of human PSD95.
Background	Postsynaptic Density protein 95 (PSD95) is a member of the membrane-associated guanylate kinase (MAGUK) family of proteins. These family members consist of an amino-terminal variable segment followed by three PDZ domains, an SH3 domain, and an inactive guanylate kinase (GK) domain. PSD95 is a scaffolding protein involved in the assembly and function of the postsynaptic density complex (1-2). PSD95 participates in synaptic targeting of AMPA receptors through an indirect manner involving stargazin and related transmembrane AMPA receptor regulatory proteins (TARPs) (3). It is implicated in experience-dependent plasticity and plays an indispensable role in learning (4). Mutations in PSD95 are associated with autism (5).

Specifications