Cell Signaling Galectin-1/Lgals1 (8a12) Mouse mAb (BSA And Azide Free)

Name: Cell Signaling Galectin-1/Lgals1 (8a12) Mouse mAb (BSA And Azide Free)
SKU: CSSPQ-88084SF
Price: 865.00 USD

List Price $865.00 Your Price $865.00

Cell Signaling Galectin-1/Lgals1 (8a12) Mouse mAb (BSA And Azide Free) - CSSPQ (Additional S&H or Hazmat Fees May Apply)

NETA PART: CSSPQ-88084SF

MFG.PART: 88084SF

UNSPSC: 12352203

Manufacturer: Cell Signaling

Description

Size	100 µg
Reactivity	H
Sensitivity	Endogenous
Molecular Weight (kDa)	15
Source/Isotype	Mouse IgG1
Application/Dilution	{}
Storage	Supplied in 1X PBS, BSA and Azide Free.For standard formulation of this product see product #40103
Specificity/Sensitivity	Galectin-1/LGALS1 (8A12) Mouse mAb (BSA and Azide Free) recognizes endogenous levels of total galectin-1 protein.
Species Reactivity	Human
Source/Purification	Monoclonal antibody is produced by immunizing animals with recombinant protein specific to human galectin-1 protein.
Background	Galectins are a family of β-galactose binding proteins that are characterized by their affinity for poly-N-acetyllactosamine-enriched glycoconjugates and their carbohydrate-binding site (1,2). Members of the galectin family have been implicated in a variety of biological functions including cell adhesion (3), growth regulation (4), cytokine production (5), T cell apoptosis (6), and immune responses (7). Galectin-1/LGALS1 has been shown to be expressed in a wide range of tissues and cell types. The level and pattern of expression of galectin-1 have been shown to change during development (8). In addition to a role in developmental processes, galectin-1 has been shown to be involved in central immune tolerance and may function in tumorigenesis by modulating the immune response to the tumor (9,10). Research studies have shown that galectin-1 expression is increased in several human cancers, suggesting a correlation with metastatic potential (10).

Specifications