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Sigma-Aldrich Ambrisentan
List Price $867.00 Your Price $867.00
Sigma-Aldrich Ambrisentan - SIALGSK (Additional S&H or Hazmat Fees May Apply)
NETA PART: SIALGSK-1019111100MG
MFG.PART: 1019111-100MG
UNSPSC: 12352202
Manufacturer: Sigma-Aldrich
grade
analytical standard
pharmaceutical primary standard
agency
USP
manufacturer/tradename
USP
application(s)
pharmaceutical small molecule
format
neat
storage temp.
2-8°C
SMILES string
CC1=CC(C)=NC(O[C@@H](C(C2=CC=CC=C2)(OC)C3=CC=CC=C3)C(O)=O)=N1
InChI
1S/C22H22N2O4/c1-15-14-16(2)24-21(23-15)28-19(20(25)26)22(27-3,17-10-6-4-7-11-17)18-12-8-5-9-13-18/h4-14,19H,1-3H3,(H,25,26)
InChI key
OUJTZYPIHDYQMC-UHFFFAOYSA-N
General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including MSDS and any product information leaflets, have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
Biochem/physiol Actions
Ambrisentan is an endothelin receptor antagonist used in the treatment of pulmonary arterial hypertension (PAH). It is 200-fold selective for the the ETA receptor subtype with a Ki of 1 nM for ETA and a Ki of 195 nM for ETB.
Endothelin ETA Receptor Antagonist; Antihypertensive; Pulmonary Hypertension Treatment
Analysis Note
These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
Other Notes
Sales restrictions may apply.
USP issued SDS can be found here
| SKU | SIALGSK-1019111100MG |
|---|---|
| Supplier Part Number | 1019111-100MG |
| UM | EA |
| UNSPSC | 12352202 |
| Manufacturer | Sigma-Aldrich |
| ProductLine | SIALGSK |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 9 |
| CAS Number | 177036-94-1 |
| Energy Star | No |
| Green | No |
| Controlled | N |