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Sigma-Aldrich Anti Activating Transcription Factor 1 &
List Price $309.00 Your Price $309.00
Sigma-Aldrich Anti Activating Transcription Factor 1 & - SIALGSK (Additional S&H or Hazmat Fees May Apply)
NETA PART: SIALGSK-SAB6012042
MFG.PART: SAB6012042-100UL
UNSPSC: 12352200
Manufacturer: Sigma-Aldrich
biological source
rabbit (Monoclonal)
Quality Level
100
recombinant
expressed in HEK 293 cells
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
23GB4325, recombinant monoclonal
form
buffered aqueous glycerol solution
mol wt
29 kDa
species reactivity
human
packaging
vial of 1.5 mL
enhanced validation
recombinant expression
Learn more about Antibody Enhanced Validation
concentration
0.537 mg/mL
technique(s)
flow cytometry: 1:2000
immunofluorescence: 1:100-:1000
western blot: 1:1,000-1:5,000
isotype
IgG
Ensembl | human accession no.
ENSG00000123268
NCBI accession no.
NP_005162.1
UniProt accession no.
P18846
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... ATF1(466)
General description
This gene encodes an activating transcription factor, which belongs to the ATF subfamily and bZIP (basic-region leucine zipper) family. It influences cellular physiologic processes by regulating the expression of downstream target genes, which are related to growth, survival, and other cellular activities. This protein is phosphorylated at serine 63 in its kinase-inducible domain by serine/threonine kinases, cAMP-dependent protein kinase A, calmodulin-dependent protein kinase I/II, mitogen- and stress-activated protein kinase and cyclin-dependent kinase 3 (cdk-3). Its phosphorylation enhances its transactivation and transcriptional activities, and enhances cell transformation. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in angiomatoid fibrous histiocytoma and clear cell sarcoma. This gene has a pseudogene on chromosome 6. [provided by RefSeq, Aug 2010]
Immunogen
A synthesized peptide corresponding to a sequence within amino acids 200-271 of human ATF1 [NP_005162.1].
Physical form
Solution in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.
Other Notes
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
| SKU | SIALGSK-SAB6012042 |
|---|---|
| Supplier Part Number | SAB6012042-100UL |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Sigma-Aldrich |
| ProductLine | SIALGSK |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 9 |
| Energy Star | No |
| Green | No |
| Controlled | N |