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Sigma-Aldrich Anti Ring Finger Protein 14 Antibody C&
List Price $309.00 Your Price $309.00
Sigma-Aldrich Anti Ring Finger Protein 14 Antibody C& - SIALGSK (Additional S&H or Hazmat Fees May Apply)
NETA PART: SIALGSK-SAB6012048
MFG.PART: SAB6012048-100UL
UNSPSC: 41116010
Manufacturer: Sigma-Aldrich
biological source
rabbit (Monoclonal)
Quality Level
100
recombinant
expressed in HEK 293 cells
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
23GB4610, recombinant monoclonal
form
buffered aqueous glycerol solution
mol wt
54 kDa
species reactivity
rat, human
packaging
vial of 1.5 mL
enhanced validation
recombinant expression
Learn more about Antibody Enhanced Validation
concentration
0.2 mg/mL
technique(s)
flow cytometry: 1:2000
immunofluorescence: 1:100-:1000
western blot: 1:1,000-1:5,000
isotype
IgG
Ensembl | human accession no.
ENSG00000013561
NCBI accession no.
NP_004281.1
UniProt accession no.
Q9UBS8
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... RNF14(9604)
General description
The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein interacts with androgen receptor (AR) and may function as a coactivator that induces AR target gene expression in prostate. A dominant negative mutant of this gene has been demonstrated to inhibit the AR-mediated growth of prostate cancer. This protein also interacts with class III ubiquitin-conjugating enzymes (E2s) and may act as a ubiquitin-ligase (E3) in the ubiquitination of certain nuclear proteins. Six alternatively spliced transcript variants encoding two distinct isoforms have been reported. [provided by RefSeq, Jan 2011]
Immunogen
A synthesized peptide corresponding to a sequence within amino acids 350-375 of human RNF14 [NP_004281.1].
Physical form
Solution in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.
Other Notes
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
| SKU | SIALGSK-SAB6012048 |
|---|---|
| Supplier Part Number | SAB6012048-100UL |
| UM | EA |
| UNSPSC | 41116010 |
| Manufacturer | Sigma-Aldrich |
| ProductLine | SIALGSK |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 9 |
| Energy Star | No |
| Green | No |
| Controlled | N |