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Sigma-Aldrich Plantamajoside
List Price $319.00 Your Price $319.00
Sigma-Aldrich Plantamajoside - SIALGSK (Additional S&H or Hazmat Fees May Apply)
NETA PART: SIALGSK-SML4276-25MG
MFG.PART: SML4276-25MG
UNSPSC: 12352200
Manufacturer: Sigma-Aldrich
Quality Level
100
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2mg/mL, clear
storage temp.
-10 to -25°C
General description
Caffeic acid glycoside derivative that exhibits anti-inflammatory, antioxidative, antiapoptotic, antiaging, as well as antitumor activities.
Plantamajoside is a caffeic acid glycoside derivative that exhibits anti-inflammatory, antioxidative, antiapoptotic, antiaging, as well as antitumor activities. Plantamajoside suppresses the production of IL-1β, IL-6 and TNF-α in a dose-dependent manner, and inhibits phosphorylation of IκBα, p65, p38, JNK and ERK. Plantamajoside also inhibits LPS-induced PI3K and AKT phosphorylation and suppresses acute lung injury in mice. It protects hypoxia-reoxygenation-induced H9c2 cardiomyocytes injury by stimulating the ILK/c-Src/Akt signaling and inhibiting the mitochondrial apoptosis pathway.
Plantamajoside is a caffeic acid glycoside derivative that exhibits anti-inflammatory, antioxidative, antiapoptotic, antiaging, as well as antitumor activities. Plantamajoside suppresses the production of IL-1β, IL-6 and TNF-α in a dose-dependent manner, and inhibits phosphorylation of IκBα, p65, p38, JNK and ERK. Plantamajoside also inhibits LPS-induced PI3K and AKT phosphorylation and suppresses acute lung injury in mice. It protects hypoxia-reoxygenation-induced H9c2 cardiomyocytes injury by stimulating the ILK/c-Src/Akt signaling and inhibiting the mitochondrial apoptosis pathway.
| SKU | SIALGSK-SML4276-25MG |
|---|---|
| Supplier Part Number | SML4276-25MG |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Sigma-Aldrich |
| ProductLine | SIALGSK |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 9 |
| CAS Number | 104777-68-6 |
| Energy Star | No |
| Green | No |
| Controlled | N |