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Sigma-Aldrich Sulbactam Sodium
List Price $117.00 Your Price $117.00
Sigma-Aldrich Sulbactam Sodium; 50 mg - SIALGSK (Additional S&H or Hazmat Fees May Apply)
NETA PART: SIALGSK-SML4181-50MG
MFG.PART: SML4181-50MG
UNSPSC: 51102800
Manufacturer: Sigma-Aldrich
Quality Level
100
assay
≥98% (HPLC)
form
powder
storage condition
desiccated
color
white to beige
solubility
H2O: 2mg/mL, clear
storage temp.
-10 to -25°C
SMILES string
O=C([C@@H]1N2[C@]([H])(S(=O)(C1(C)C)=O)CC2=O)O[Na]
Application
Sulbactam sodium may be used for in vitro antibacterial efficacy analysis.
Biochem/physiol Actions
Sulbactam is a competitive, irreversible β-lactamase inhibitor that enhances β-lactam antibiotics′ efficacy.
Sulbactam sodium, the sodium salt form of sulbactam, is water-soluble and exhibits enhanced hydrophilicity and is better suited for formulations involving aqueous media. In its capacity as a β-lactamase inhibitor, sulbactam sodium synergistically augments the antimicrobial efficacy of β-lactam antibiotics against recalcitrant bacterial pathogens. This synergistic effect is achieved through an irreversible covalent interaction between sulbactam and the β-lactamase enzymes, which are responsible for the degradation and consequent inactivation of β-lactam antibiotics. Additionally, sulbactam sodium demonstrates inherent antibacterial activity, albeit with a relatively lower potency compared to other members of the β-lactam antibiotic class.
Sulbactam sodium, the sodium salt form of sulbactam, is water-soluble and exhibits enhanced hydrophilicity and is better suited for formulations involving aqueous media. In its capacity as a β-lactamase inhibitor, sulbactam sodium synergistically augments the antimicrobial efficacy of β-lactam antibiotics against recalcitrant bacterial pathogens. This synergistic effect is achieved through an irreversible covalent interaction between sulbactam and the β-lactamase enzymes, which are responsible for the degradation and consequent inactivation of β-lactam antibiotics. Additionally, sulbactam sodium demonstrates inherent antibacterial activity, albeit with a relatively lower potency compared to other members of the β-lactam antibiotic class.
Disclaimer
Hygroscopic Store with desiccant
| SKU | SIALGSK-SML4181-50MG |
|---|---|
| Supplier Part Number | SML4181-50MG |
| UM | EA |
| UNSPSC | 51102800 |
| Manufacturer | Sigma-Aldrich |
| ProductLine | SIALGSK |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 9 |
| CAS Number | 69388-84-7 |
| Energy Star | No |
| Green | No |
| Controlled | N |