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Sigma-Aldrich Phenoxodiol
List Price $599.00 Your Price $599.00
Sigma-Aldrich Phenoxodiol - SIALGSK (Additional S&H or Hazmat Fees May Apply)
NETA PART: SIALGSK-SML4239-25MG
MFG.PART: SML4239-25MG
UNSPSC: 41105500
Manufacturer: Sigma-Aldrich
Quality Level
100
assay
≥98% (HPLC)
form
powder
color
white to pink
solubility
DMSO: 2mg/mL, clear
storage temp.
2-8°C
Biochem/physiol Actions
Pan-cancer drug; causes apoptosis via both intrinsic and extrinsic pathways; targets plasma membrane electron transport (PMET); inhibits tumor-specific NADH oxidase tNOX (ENOX2).
Phenoxodiol, an isoflavene, is a broad-spectrum anti-tumor agent that causes apoptosis via both intrinsic and extrinsic pathways. It acts as a potent sensitizer of most standard chemotoxic agents. Phenoxodiol inhibits tumor-specific NADH oxidase tNOX (ENOX2). It blocks phosphorylation and activation of several different pro-survival signaling proteins including sphingosine kinase and Akt.
Phenoxodiol, an isoflavene, is a broad-spectrum anti-tumor agent that causes apoptosis via both intrinsic and extrinsic pathways. It acts as a potent sensitizer of most standard chemotoxic agents. Phenoxodiol inhibits tumor-specific NADH oxidase tNOX (ENOX2). It blocks phosphorylation and activation of several different pro-survival signaling proteins including sphingosine kinase and Akt.
| SKU | SIALGSK-SML4239-25MG |
|---|---|
| Supplier Part Number | SML4239-25MG |
| UM | EA |
| UNSPSC | 41105500 |
| Manufacturer | Sigma-Aldrich |
| ProductLine | SIALGSK |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 9 |
| CAS Number | 81267-65-4 |
| Energy Star | No |
| Green | No |
| Controlled | N |