Sigma-Aldrich DMT-2O-ME-RA(BZ) AMIDITE mm

Name: Sigma-Aldrich DMT-2O-ME-RA(BZ) AMIDITE mm
SKU: SIALGSK-A211140-10G
Price: 346.00 USD

List Price $346.00 Your Price $346.00

Sigma-Aldrich DMT-2′O-Methyl-rA(bz) Phosphoramidite, configured for MerMade - SIALGSK (Additional S&H or Hazmat Fees May Apply)

NETA PART: SIALGSK-A211140-10G

MFG.PART: A211140-10G

UNSPSC: 41116105

Manufacturer: Sigma-Aldrich

Description

biological source
non-animal source (no BSE/TSE risk)

Quality Level
300

product line
Proligo Reagents

assay
≥99% (³¹P-NMR) ≥99.0% (redox titration)

form
powder

impurities
≤0.3% mA2 (reversed phase HPLC, Hydrolysate) ≤0.3% mA3 (reversed phase HPLC, DMT-rA(bz)me) ≤0.3% water content (Karl Fischer) ≤0.5% P(III) Impurities 100-169ppm (³¹P-NMR) ≤0.5% single Impurity (redox titration) ≤1.0% mA1 (reversed phase HPLC, DMT-rA(bz)me-DMT) ≤3% residual Solvent content

color
white to off-white

suitability
conforms to structure for H-NMR conforms to structure for LC-MS

compatibility
configured for MerMade

storage temp.
-10 to -25°C

General description

High yield of crude oligonucleotides
Compatible with DNA synthesis
Can be employed together with DNA or RNA phosphoramidites in thesame synthesis to produce mixmer oligonucleotides
Recommended deprotection conditions are 8 hours at 55 °C usingconcentrated ammonia solution, or with AMA (concentrated ammonia/40% aqueous methylamine I/I, v/v) for 10 minutes at 65 °C
Purification and other downstream processing of fully modified 2′OMethyl RNA oligonucleotides are simpler than in the case of RNA, as nospecial precautions are required to provide protection against nucleolyticdegradationDMT-2′O-Methyl-rA(bz) Phosphoramidite is configured for MerMade Synthesizers.

Specifications