Revvity HTRF Human Ki-67 kit, 500 Tests

The expression of the proliferation related nuclear antigen Ki-67, also known as Ki67 or MKI67, is a cellular marker for proliferation which is only detected in dividing cells. Ki-67 is a non-histone protein characterized as a nuclear matrix-associated proliferation-related antigen present throughout the cell cycle, but not in resting, quiescent, cells (G0 phase). Ki-67 is widely used in routine pathology as a proliferation marker to measure the growth fraction of cells in human tumors. The Ki-67 protein present in the nucleus of proliferating cells is released upon cell lysis, and the Ki-67 protein extracted in the lysate is quantified using our Ki-67 HTRF assay. The Ki-67 quantitation assay is an alternative to BrdU or EdU incorporation assays, which are exogenous proliferation markers incorporated into the newly synthesized DNA of dividing cells. The scope of Ki-67 is similar to that of the proliferating cell nuclear antigen (PCNA).