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Revvity HTRF Human XBP1s Detection Kit, 10,000 Assay Points
List Price $16,197.09 Your Price $16,197.09
Revvity HTRF Human XBP1s Detection Kit, 10,000 Assay Points - REV
NETA PART: REV-64XBPSTPEH
MFG.PART: 64XBPSTPEH
UNSPSC: 41116126
Manufacturer: Revvity
Upon ER stress and accumulation of unfolded proteins, BiP releases its inhibitory binding to activate IRE1. IRE1 receptor dimerizes then autophosphorylates which activates its mRNase activity. Through this action, IRE1 splices XBP-1u mRNA to XBP1s, enabling its translation and then its translocation to the nucleus. XBP-1s then acts as a transcription factor.
The HTRF XBP1s detection assay monitors spliced XBP1s, and is used to detect the expression of endogenous or overexpressed XBP1s.
| SKU | REV-64XBPSTPEH |
|---|---|
| Supplier Part Number | 64XBPSTPEH |
| UM | EA |
| UNSPSC | 41116126 |
| Manufacturer | Revvity |
| CountryOfOrigin | France |
| ProductLine | REV |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| Energy Star | No |
| Green | No |
| Controlled | N |