Revvity HTRF Human Total Myd88 Detection Kit, 500 Assay Points

Revvity Myeloid differentiation factor 88 (MyD88) is a central adaptor for Toll-like or interleukin-1 Receptors (TLR/IL-1R) signaling that mediates initiation of the innate immune response and production of the proinflammatory cytokines that restrain pathogens and activate adaptive immunity. Although MyD88 is crucial for a host to prevent pathogenic infection, misregulation of its abundance might lead to autoimmune diseases. Degradation of MyD88 is a key canonical mechanism for terminating cytokine production. - REV