Revvity HTRF Human & mouse Total STAT5 Detection Kit, 500 Assay Points

Signal Transducer and Activator of Transcription (STAT) proteins are a seven-member family of cytoplasmic transcription factors that relay signals emanating from cell-surface cytokine and growth factor receptors to the nucleus. STAT proteins control fundamental cellular processes, including cell survival, proliferation, differentiation, and immune responses. Dysregulation of STAT5 signaling is implicated in hematopoietic cancers, where it promotes cell survival, proliferation, and metastasis.