Revvity HTRF Utrophin Detection Kit, 10,000 Assay Points

Utrophin is an autosomally-encoded 376-kDa cytoskeletal protein that is similar in structure and function to dystrophin. It is a ubiquitously expressed protein that plays a role in anchoring the cytoskeleton to the plasma membrane. Utrophin is highly expressed in developing muscle, and is enriched at the neuromuscular junction of mature muscle. Duchennes muscular dystrophy patients lack dystrophin, and utrophin is consequently up-regulated and redistributed to locations normally occupied by dystrophin. HTRF Utrophin kit is designed for its rapid detection in cell lysates.​​​​​​​