Revvity HTRF Human CCL22 Detection kit, 500 Assay Points

CCL22 (C-C motif chemokine 22), previously referred to as Macrophage-derived chemokine (MDC), is a chemokine secreted by dendritic cells (DC), macrophages, and activated B-lymphocytes. CCL22 binds to CCR4 present in many different cell types.

CCL22 is secreted by M2 macrophages, which contribute to Th2 responses such as phagocytosis, tissue repair, and wound healing.

Through its binding to CCR4, CCL22 has also been shown to contribute to the pathogenesis of atopic diseases, like asthma and atopic dermatitis (AD).

Assessment of serum samples often requires enhanced sensitivity. In some cases, AlphaLISA assays may have sufficient sensitivity to enable the detection of low levels of analytes in serum or plasma. When assaying, always follow the recommended protocol and avoid highly haemolyzed samples.