Revvity IVISense Toxicology Fluorescent Imaging Panel

Our Toxicology Fluorescent Imaging Panel of probes allows you to image inflammation, tissue destruction, metabolic changes, and vascular leak (edema), in a manner that can be predictive of potential drug toxicity, measuring biological changes prior to overt histological signs. Our published research shows the utility of a three-probe cocktail for imaging drug-induced liver injury (Vasquez & Peterson, J Pharmacol Exp Ther 2017; 361:87-98) via a ratio of probes specifically designed to optimize liver injury signal while minimizing normal background signal in liver and kidneys. The Toxicology Panel provides an extra vial of IVISense MMP 750 FAST to allow the preparation of the cocktail.

The inclusion of probes at 680 nm and 750 nm wavelengths further offers the opportunity for multiplex imaging of appropriate probe combinations to maximize information gained from research animals.