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Revvity HTRF Human Phospho-PLC-γ2 (Tyr1217) Detection Kit, 50,000 Assay Points
List Price $52,530.00 Your Price $52,530.00
Revvity HTRF Human Phospho-PLC-γ2 (Tyr1217) Detection Kit, 50,000 Assay Points - REV
NETA PART: REV-64PLCG2Y7PEY
MFG.PART: 64PLCG2Y7PEY
UNSPSC: 41122102
Manufacturer: Revvity
This HTRF cell-based assay conveniently and accurately detects phosphorylated Phospholipase C gamma 2 (PLCgamma 2) at Tyr1217.
PLCgamma 2 is a phosphoinositide-specific phospholipase that generates second messengers and plays a crucial role in signal transduction, especially in haematopoietic cells such as B cells, mast cells, macrophages, natural killer cells and platelets. Upon stimulation of different receptors such as B-cell antigen receptor (BCR) and Fc receptors (FcRs), PLCgamma 2 interacts with several adapter proteins and becomes phosphorylated by intracellular tyrosine kinases. Phosphorylation includes several sites, one of which is Tyr1217.
PLCgamma 2 has been linked to various pathologies such as auto-immune and inflammatory diseases, drug-resistance in cancer and neurodegeneration.
| SKU | REV-64PLCG2Y7PEY |
|---|---|
| Supplier Part Number | 64PLCG2Y7PEY |
| UM | EA |
| UNSPSC | 41122102 |
| Manufacturer | Revvity |
| CountryOfOrigin | France |
| ProductLine | REV |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| Energy Star | No |
| Green | No |
| Controlled | N |