Revvity HTRF Human IL-4 Detection Kit, 100,000 Assay Points

IL4 is expressed by T cells, NK cells, and mast cells, and is an important regulator of humoral and adaptative immunity. It stimulates activated B cells, and induces IR differentiation into plasma cells and IR class switch to immunoglobulin E, as well as promoting class II MHC expression. In immuno-oncology, IL4 induces differentiation of naïve T cells into TH2 cells, which in turn produce IL4 and thus create a positive feedback loop. IL4 is also involved in development of airway inflammation and allergic asthma.

Assessment of serum samples often requires enhanced sensitivity. In some cases, AlphaLISA assays may have sufficient sensitivity to enable detection of low levels of analytes in serum or plasma.