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Revvity HTRF Human H232 STING Binding Kit, 100,000 Assay Points
List Price $188,550.00 Your Price $188,550.00
Revvity HTRF Human H232 STING Binding Kit, 100,000 Assay Points - REV
NETA PART: REV-64BDSTGHPEJ
MFG.PART: 64BDSTGHPEJ
UNSPSC: 41122102
Manufacturer: Revvity
A fast and easy way to identify new binders to human H232 STING.
Stimulator of interferon genes (STING), also known as transmembrane protein 173 (TMEM173), is a protein playing a major role in innate immunity.
The H232 variant is found in 13.7% of the world population. Upon intracellular cytosolic DNA release from pathogens such as viruses and bacteria, 2â-3âcGAMP binds to STING protein and triggers the secretion of type 1 interferon. However, the H232 variant is known to poorly bind 2-3cGAMP and other natural dinucleotides. The quest for molecules that are effective against all genetic variants has become crucial to modulate immunity in autoinflammatory diseases.
| SKU | REV-64BDSTGHPEJ |
|---|---|
| Supplier Part Number | 64BDSTGHPEJ |
| UM | EA |
| UNSPSC | 41122102 |
| Manufacturer | Revvity |
| CountryOfOrigin | France |
| ProductLine | REV |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| Energy Star | No |
| Green | No |
| Controlled | N |