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Revvity HTRF Human & Mouse Total EIF2α Detection Kit, 50,000 Assay Points
List Price $52,530.00 Your Price $52,530.00
Revvity HTRF Human and Mouse Total EIF2α Detection Kit, 50,000 Assay Points - REV
NETA PART: REV-64NEFPEY
MFG.PART: 64NEFPEY
UNSPSC: 41122102
Manufacturer: Revvity
The Total EIF2 alpha cellular assay monitors total EIF2 alpha and is used as a normalization assay with the phospho-EIF2 alpha kit. In NASH, lipid accumulation in hepatocytes (steatosis) induces oxidative and ER stresses, resulting in an increase of Phospho-EIF2alpha (Ser52). Phosphorylated EIF2 alpha reduces global protein synthesis and activates ATF4 (Activating Transcription Factor 4), which modulates the expression of specific genes involved in the regulation of metabolism, nutrient uptake, the redox status of cells, and apoptosis.
| SKU | REV-64NEFPEY |
|---|---|
| Supplier Part Number | 64NEFPEY |
| UM | EA |
| UNSPSC | 41122102 |
| Manufacturer | Revvity |
| CountryOfOrigin | France |
| ProductLine | REV |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| Energy Star | No |
| Green | No |
| Controlled | N |