Revvity PhenoVue 488 Lysosomal Stain

Lysosomes are abundant organelles which contain more than sixty acidic enzymes. Lysosomes play an essential role in macromolecule and organelle break down through the autophagy-lysosomal system. Defective regulation of lysosomal function has been reported in several diseases, such as lysosomal storage disorders and neurodegenerative diseases, including Alzheimer’s and Parkinson’s. PhenoVue 488 lysosomal stain is a pH-sensitive probe which accumulates in acidic vesicles such as lysosomes, resulting in bright and specific lysosomal fluorescent staining. PhenoVue 488 lysosomal stain can be used to visualize lysosomes in immunofluorescence, as well as high-content analysis and screening applications.

Equivalent number of microplates:

• 0.8-2.5 x 96-well microplates
• 0.7-2.5 x 384-well microplates
• 1.3-4 x 1536-well microplates