Revvity HTRF Human Phospho-STAT2 (Tyr690) Detection Kit, 50,000 assay points

STAT2 (Signal transducer and activator of transcription 2) is a member of the cytoplasmic transcription factors family that relay signals emanating from cell-surface cytokine and growth factor receptors to the nucleus. STAT proteins control fundamental cellular processes, including cell survival, proliferation, differentiation, and immune responses. Dysregulation of STAT2 signaling has been implicated in various diseases, particularly viral infections and immune disorders.

HTRF assays offer many advantages over other technologies:

• Homogeneous add-and-read format
• No wash steps
• Low background
• Straightforward miniaturization from 96- or 384-well microplates to high density assay formats such as 384-well low volume and 1536-well plates
• Stable signal, providing flexibility in time of readout or size of assays