Revvity pHSense Mouse IgG2a Isotype Control, 50 µg

pHSense Eu Fab reagents are designed to monitor antibody or anti-drug conjugate (ADC), as well as receptor- and membrane protein-mediated internalization in real time. To confidently attribute observed effects to specific antigen binding, it is crucial to include proper controls. Test antibodies may engage in non-specific interactions - particularly when their Fc regions bind to Fc receptors on cells - which can contribute to background signal. This is where negative control antibodies become essential in pHSense assays. They help distinguish true signal from background noise by revealing non-specific binding effects, thereby enhancing the reliability of your internalization measurements.

The pHSense Mouse IgG2 Negative Control is a purified mouse IgG2 antibody. It serves as an ideal isotype control when evaluating mouse IgG2 antibodies in conjunction with pHSense reagents.