Revvity HTRF Human TREM2 (Full-Length) Detection Kit, 500 Assay Points

The kit is designed for the rapid detection of the full-length TREM2 receptor by using two antibodies that target distinct regions, the extracellular domain and the intracellular region, allowing detection before receptor shedding by ADAM10 and ADAM17 proteases. TREM2 (Triggering Receptor Expressed on Myeloid Cells 2) belongs to the TREM family of receptors, which regulate the activity of various immune cell types, including neutrophils, monocytes/macrophages, microglia, and dendritic cells.

HTRF assays offer many advantages over other technologies:

• Homogeneous add-and-read format
• No wash steps
• Low background
• Straightforward miniaturization from 96- or 384-well microplates to high density assay formats such as 384-well low volume and 1536-well plates
• Stable signal, providing flexibility in readout time or size of assays