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Cayman α-Humulene


Product Description
α-Humulene is a sesquiterpene that has been found in C. sativa, C. indica, and hemp with diverse biological activities.1,2,3,4,5 It is lethal to A. subpictus, A. albopictus, and C. tritaeniorhynchus mosquito larvae (LC50s = 6.19, 7.39, and 12.05 mg/mL, respectively).2 α-Humulene reduces growth of MCF-7 breast cancer cells by approximately 50% when used at a concentration of 32 mg/mL.3 It also reduces viability of Caco-2 cells in a concentration-dependent manner (IC50 = 24.4 mg/mL) but has no effect on viability of rat hepatocytes.4 In vivo, α-humulene (50 mg/kg) reduces histamine-induced paw edema in mice as well as carrageenan-induced TNF-α and IL-1β production and paw edema in mice and rats.5 It also reduces carrageenan-induced production of prostaglandin E2 (PGE2) and expression of inducible nitric oxide synthase (iNOS) and COX-2 in rats.
WARNING This product is not for human or veterinary use.
Technical Information
- α-
Caryophyllene - (±)-α-
Humulene
- Methanol: 10 mg/mL
Shipping & Storage Information
| SKU | CAYM-21574-500 |
|---|---|
| Supplier Part Number | 21574-500 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 6753-98-6 |
| Energy Star | No |
| Green | No |
| Controlled | N |

