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Cayman Enterobactin
Product Description
Paraxanthine-d6 is intended for use as an internal standard for the quantification of paraxanthine (Item No. ) by GC- or LC-MS. Paraxanthine is an active metabolite of caffeine (Item No. ). It is formed via N3-demethylation of caffeine by the cytochrome P450 (CYP) isoform CYP1A2. Paraxanthine is an adenosine A1 and A2 receptor antagonist (Kis = 35 and 22 µM, respectively). In vivo, paraxanthine (30 mg/kg) increases striatal cGMP and extracellular striatal dopamine levels and locomotor activity, as well as inhibits motor depression induced by the adenosine A1 agonist CPA (N6-cyclopentyladenosine; Item No. ) or the adenosine A2 receptor agonist CGS 21680 (Item No. ) in rats not habituated to caffeine. It also promotes wakefulness and increases locomotor activity and core temperature in narcoleptic transgenic mice without increasing behavioral anxiety.
WARNING This product is not for human or veterinary use.
Technical Information
- 1,7-Dimethylxanthine-d6
- DMF: 10 mg/ml
- DMSO: 10 mg/ml
- Ethanol: 1 mg/ml
- PBS (pH 7.2): 1 mg/ml
Shipping & Storage Information
| SKU | CAYM-33394-1 |
|---|---|
| Featured | No |
| Supplier Part Number | 33394-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 28384-96-5 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |