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Cayman Fz7-21 (trifluoroacetate salt)
List Price $482.00 Your Price $482.00
Cayman Fz7-21 (trifluoroacetate salt) - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-36922-25
MFG.PART: 36922-25
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
Fz7-21 is a peptide antagonist of the frizzled family g protein-coupled receptor 7 (FZD7; IC50 = 100 nM).1 It inhibits Wnt3a-induced β-catenin signaling in a reporter assay using HEK293 cells. Fz7-21 (100 µM) reduces the number of cells positive for leucine-rich α-2-glycoprotein 5 (Lrg5), a marker of intestinal stem cells, and the mRNA encoding achaete-scute homolog 2 (Ash-2) and Axin2 and increases mRNA encoding mucin 2 (Muc2) in primary mouse intestinal organoids.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-acetyl-L-
Synonyms
- dFz7-21
Molecular Formula
C83H114N18O23S2 • XCF3COOH
Formula Weight
1796.0
Purity
≥98%
Formulation(Request formulation change)
A solid
Peptide Sequence
AC-LPSDDLEFWCHVMY-NH2
Solubility(Learn about Variance in Solubility)
- DMF: 10 mg/mL
- DMSO: 10 mg/mL
SMILES
O=C([C@H]1N(CCC1)C([C@@H](NC(C)=O)CC(C)C)=O)N[C@@H](CO)C(N[C@@H](CC(O)=O)C(N[C@@H](CC(O)=O)C(N[C@@H](CC(C)C)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC2=CC=CC=C2)C(N[C@H](C(N[C@@H](CS)C(N[C@H](C(N[C@@H](C(C)C)C(N[C@@H](CCSC)C(N[C@H](C(N)=O)CC3=CC=C(C=C3)O)=O)=O)=O)CC4=CN=CN4)=O)=O)CC5=CNC6=CC=CC=C56)=O)=O)=O)=O)=O)=O.OC(C(F)(F)F)=O
InChi Code
InChI=1S/C83H114N18O23S2.C2HF3O2/c1-42(2)29-56(92-76(117)60(35-67(107)108)96-77(118)61(36-68(109)110)97-79(120)63(39-102)98-81(122)65-19-14-27-101(65)83(124)62(30-43(3)4)88-45(7)103)73(114)89-53(24-25-66(105)106)71(112)93-57(32-46-15-10-9-11-16-46)74(115)94-58(33-48-37-86-52-18-13-12-17-51(48)52)75(116)99-64(40-125)80(121)95-59(34-49-38-85-41-87-49)78(119)100-69(44(5)6)82(123)90-54(26-28-126-8)72(113)91-55(70(84)111)31-47-20-22-50(104)23-21-47;3-2(4,5)1(6)7/h9-13,15-18,20-23,37-38,41-44,53-65,69,86,102,104,125H,14,19,24-36,39-40H2,1-8H3,(H2,84,111)(H,85,87)(H,88,103)(H,89,114)(H,90,123)(H,91,113)(H,92,117)(H,93,112)(H,94,115)(H,95,121)(H,96,118)(H,97,120)(H,98,122)(H,99,116)(H,100,119)(H,105,106)(H,107,108)(H,109,110);(H,6,7)/t53-,54-,55-,56-,57-,58-,59-,60-,61-,62-,63-,64-,65-,69-;/m0./s1
InChi Key
XNOVOOBFDJIKMU-OJNHWORCSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-36922-25 |
|---|---|
| Supplier Part Number | 36922-25 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| Energy Star | No |
| Green | No |
| Controlled | N |