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Cayman HMN-176
List Price
$91.00
Your Price
$91.00
Cayman HMN-176 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-37424-5
MFG.PART:
37424-5
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
HMN-176 is an anticancer agent and active metabolite of the prodrug HMN-214 (Item No. 26210).1 It is cytotoxic against a panel of cancer cell lines with a mean IC50 value of 112 nM, as well as P388 leukemia cells that are resistant to the DNA-crosslinking agent cisplatin (Item No. 13119), anthracycline antitumor antibiotic doxorubicin (Item No. 15007), or antimitotic vincristine (Item No. 11764) (IC50s = 143, 557, and 265 nM, respectively). HMN-176 (3 µM) induces cell cycle arrest at the G2/M phase in HeLa cervical cancer cells.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
4-methoxy-N-[2-
CAS Number
173529-10-7
Molecular Formula
C20H18N2O4S
Formula Weight
382.4
Purity
≥98%
Formulation(Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
- DMF: 10 mg/mL
- DMSO: 10 mg/mL
λmax
239, 343 nm
SMILES
O=S(NC1=C(C=CC=C1)/C=C/C(C=C2)=CC=N2=O)(C3=CC=C(C=C3)OC)=O
InChi Code
InChI=1S/C20H18N2O4S/c1-26-18-8-10-19(11-9-18)27(24,25)21-20-5-3-2-4-17(20)7-6-16-12-14-22(23)15-13-16/h2-15,21H,1H3/b7-6+
InChi Key
LBPNULPSVCDYRF-VOTSOKGWSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-37424-5 |
|---|---|
| Featured | No |
| Supplier Part Number | 37424-5 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 173529-10-7 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |