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Cayman Bictegravir (sodium salt)
List Price
$127.00
Your Price
$127.00
Cayman Bictegravir (sodium salt) - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-37488-10
MFG.PART:
37488-10
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Bictegravir is an inhibitor of HIV-1 integrase (IC50 = 7.5 nM for strand transfer activity).1 It has antiviral activity against clinical isolates of HIV-1 in human peripheral blood mononuclear cells (PBMCs; EC50s = 0.04-1.7 nM). Bictegravir also inhibits HIV-1 viral infection in MT-2 and MT-4 cells, CD4+ T cells, and macrophages (EC50s = 1.5, 2.5, 1.5, and 6.6 nM, respectively) without exhibiting cytotoxicity (CC50s = 10.3, 3.7, 13, and 29.8 μM, respectively). Formulations containing bictegravir in combination with emtricitabine and tenofovir alafenamide have been used in the treatment of HIV-1 infections.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
2,3,4,5,7,9,
CAS Number
1807988-02-8
Synonyms
- GS-9883
Molecular Formula
C21H17F3N3O5 • Na
Formula Weight
471.4
Purity
≥95%
Formulation(Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
- Methanol: Soluble
SMILES
O=C1N2[C@@](O[C@H]3C[C@@H]2CC3)([H])CN4C1=C(C(C(C(NCC5=C(C=C(C=C5F)F)F)=O)=C4)=O)[O-].[Na+]
InChi Code
InChI=1S/C21H18F3N3O5.Na/c22-9-3-14(23)12(15(24)4-9)6-25-20(30)13-7-26-8-16-27(10-1-2-11(5-10)32-16)21(31)17(26)19(29)18(13)28;/h3-4,7,10-11,16,29H,1-2,5-6,8H2,(H,25,30);/q;+1/p-1/t10-,11+,16+;/m0./s1
InChi Key
WJNFBIVCQMPPJC-FQYDJHLKSA-M
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-37488-10 |
|---|---|
| Featured | No |
| Supplier Part Number | 37488-10 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 1807988-02-8 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |