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Cayman DC-LC3in-D5
List Price
$689.00
Your Price
$689.00
Cayman DC-LC3in-D5 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-38339-10
MFG.PART:
38339-10
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
DC-LC3in-D5 is an inhibitor of LC3 (IC50 = 200 nM).1 It selectively binds to LC3-I and LC3-II over GABA type A receptor-associated protein (GABARAP), scavenger receptor class B member 2 (SCARB2), and paraoxonase 2 (PON2) in an activity-based protein profiling (ABPP) assay using HeLa cells. DC-LC3in-D5 (25 µM) inhibits LC3-II lipidation, autophagosome formation, and the protein-protein interaction between LC3-II and ATG7 in HeLa cells.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
5-(2,3- dichloro phenyl)-2- [[[2-(4- morpholinyl) ethyl]amino] methylene]- 1,3-cyclo hexanedione
CAS Number
2868312-73-4
Molecular Formula
C19H22Cl2N2O3
Formula Weight
397.3
Purity
≥95%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- Chloroform: Soluble
- Methanol: Slightly Soluble
λmax
257, 305 nm
SMILES
O=C1/C(C(CC(C1)C2=C(Cl)C(Cl)=CC=C2)=O)=C/NCCN3CCOCC3
InChi Code
InChI=1S/C19H22Cl2N2O3/c20-16-3-1-2-14(19(16)21)13-10-17(24)15(18(25)11-13)12-22-4-5-23-6-8-26-9-7-23/h1-3,12-13,22H,4-11H2/b15-12-
InChi Key
QWRGQCLNVZLPJO-QINSGFPZSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 2 years
| SKU | CAYM-38339-10 |
|---|---|
| Featured | No |
| Supplier Part Number | 38339-10 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 2868312-73-4 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |