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Cayman DNCA
List Price
$219.00
Your Price
$219.00
Cayman DNCA - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-38554-1
MFG.PART:
38554-1
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
DNCA is a neutral lipid that has been used in the generation of lipid nanoparticles (LNPs).1 Intravenous administration of LNPs containing DNCA and encapsulating siRNA targeting BRAF containing a valine-to-glutamate substitution at position 600 (BRAFV600E) reduce tumor BRAFV600E expression and tumor weight and volume without reducing animal weight in an A375 melanoma mouse xenograft model. Intratumoral administration of LNPs containing DNCA and encapsulating cyclic di-GMP (Item No. 17144) decreases tumor volume, increase survival, and increase the ratio of tumor-associated cytotoxic/exhausted CD4+ and CD8+ T cells in an EO771 murine model of primary breast cancer with tumor rechallenge.2
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
4-amino-N-
CAS Number
2226561-66-4
Molecular Formula
C45H82N4O4
Formula Weight
743.2
Purity
≥95%
Formulation(Request formulation change)
A solution in ethanol
Solubility(Learn about Variance in Solubility)
- Ethanol: 5 mg/mL
SMILES
NC1=NC(N(CC(NCC(COCCCCCCCC/C=C\CCCCCCCC)OCCCCCCCC/C=C\CCCCCCCC)=O)C=C1)=O
InChi Code
InChI=1S/C45H82N4O4/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-37-52-41-42(39-47-44(50)40-49-36-35-43(46)48-45(49)51)53-38-34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h17-20,35-36,42H,3-16,21-34,37-41H2,1-2H3,(H,47,50)(H2,46,48,51)/b19-17-,20-18-
InChi Key
YFNQKYRJAJXRSL-CLFAGFIQSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 3 years
| SKU | CAYM-38554-1 |
|---|---|
| Supplier Part Number | 38554-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | Y |
| CAS Number | 2226561-66-4 |
| Energy Star | No |
| Green | No |
| Controlled | N |