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Cayman AA-T3A-C12
List Price
$74.00
Your Price
$74.00
Cayman AA-T3A-C12 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-38648-1
MFG.PART:
38648-1
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
AA-T3A-C12 is an ionizable cationic lipidoid that contains a polyamine core, tethered to the sigma receptor ligand anisamide, and four 12-carbon tails.1 It has been used in the generation of lipid nanoparticles (LNPs). LNPs containing AA-T3A-C12 and encapsulating siRNA for Hsp47, a molecular chaperone whose expression is increased in liver fibrosis, reduce the expression of Hsp47 in activated NIH3T3 mouse liver fibroblasts and primary mouse hepatic stellate cells, which both express high levels of the sigma receptor. LNPs containing AA-T3A-C12 and encapsulating Hsp47 siRNA reduce liver fibrosis induced by carbon tetrachloride (CCl4) in mice.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-(3-(bis(3-(bis(2-hydroxydodecyl)amino)propyl)amino)propyl)-4-methoxybenzamide
CAS Number
2938207-23-7
Molecular Formula
C65H126N4O6
Formula Weight
1059.7
Purity
≥95%
Formulation(Request formulation change)
A solution in ethanol
Solubility(Learn about Variance in Solubility)
- Ethanol: 10 mg/ml
λmax
254 nm
SMILES
O=C(C1=CC=C(OC)C=C1)NCCCN(CCCN(CC(O)CCCCCCCCCC)CC(O)CCCCCCCCCC)CCCN(CC(O)CCCCCCCCCC)CC(O)CCCCCCCCCC
InChi Code
InChI=1S/C65H126N4O6/c1-6-10-14-18-22-26-30-34-41-60(70)55-68(56-61(71)42-35-31-27-23-19-15-11-7-2)53-39-51-67(50-38-49-66-65(74)59-45-47-64(75-5)48-46-59)52-40-54-69(57-62(72)43-36-32-28-24-20-16-12-8-3)58-63(73)44-37-33-29-25-21-17-13-9-4/h45-48,60-63,70-73H,6-44,49-58H2,1-5H3,(H,66,74)
InChi Key
ADWWRKPNPJUOGO-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 1 year
| SKU | CAYM-38648-1 |
|---|---|
| Featured | No |
| Supplier Part Number | 38648-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | Y |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |