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Cayman Beclomethasone Dipropionate
List Price
$134.00
Your Price
$134.00
Cayman Beclomethasone Dipropionate - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-38880-500
MFG.PART:
38880-500
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Beclomethasone dipropionate is a glucocorticoid receptor agonist and prodrug form of beclomethasone 17-propionate (Item No. 38884).1,2 Beclomethasone dipropionate is converted to beclomethasone 17-propionate or beclomethasone 21-propionate via esterases, which are subsequently hydrolyzed to beclomethasone (Item No. 33196).1 It binds to the glucocorticoid receptor (IC50 = 2.4 nM) and inhibits glucocorticoid receptor transrepression induced by phorbol 12-myristate 13-acetate (PMA; Item No. 10008014), as well as induces transactivation of the glucocorticoid receptor, in CV-1 cells expressing the human receptor.2 Formulations containing beclomethasone dipropionate have been used in the treatment of asthma.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
9-chloro-11β-
CAS Number
5534-09-8
Synonyms
- BC-DP
- BDP
- Beclomethasone 17,21-dipropionate
Molecular Formula
C28H37ClO7
Formula Weight
521.0
Purity
≥98%
Formulation(Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
- DMF: 10 mg/ml
- DMSO: 10 mg/ml
- Ethanol: 10 mg/ml
λmax
240 nm
SMILES
C[C@@]12[C@@](OC(CC)=O)(C(COC(CC)=O)=O)[C@@H](C)C[C@@]1([H])[C@@]3([H])[C@]([C@H](C2)O)([C@@]4(C(CC3)=CC(C=C4)=O)C)Cl
InChi Code
InChI=1S/C28H37ClO7/c1-6-23(33)35-15-22(32)28(36-24(34)7-2)16(3)12-20-19-9-8-17-13-18(30)10-11-25(17,4)27(19,29)21(31)14-26(20,28)5/h10-11,13,16,19-21,31H,6-9,12,14-15H2,1-5H3/t16-,19-,20-,21-,25-,26-,27-,28-/m0/s1
InChi Key
KUVIULQEHSCUHY-XYWKZLDCSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-38880-500 |
|---|---|
| Featured | No |
| Supplier Part Number | 38880-500 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | Canada |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 5534-09-8 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |