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Cayman HUP-55
List Price $237.00 Your Price $237.00
Cayman HUP-55 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-39117-10
MFG.PART: 39117-10
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
HUP-55 is an inhibitor of prolyl endopeptidase (IC50 = 5 nM).1 It reduces α-synuclein dimerization in Neuro2a cells, induces autophagy in HEK293 cells, and decreases hydrogen peroxide-induced increases in reactive oxygen species (ROS) production in SH-SY5Y cells when used at a concentration of 10 µM. HUP-55 (10 mg/kg) decreases ipsilateral paw use and striatal oligomeric α-synuclein levels in a mouse model of Parkinson’s disease induced by adenoviral delivery of an α-synuclein-encoding vector (AAV-αSyn).
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
(S)-1-(4-
Molecular Formula
C18H21N3O
Formula Weight
295.4
Purity
≥98%
Formulation(Request formulation change)
A solution in acetonitrile
Solubility(Learn about Variance in Solubility)
- Acetonitrile: 10 mg/mL
SMILES
CC1=C(N2[C@H](C#N)CCC2)OC(CCCC3=CC=CC=C3)=N1
InChi Code
InChI=1S/C18H21N3O/c1-14-18(21-12-6-10-16(21)13-19)22-17(20-14)11-5-9-15-7-3-2-4-8-15/h2-4,7-8,16H,5-6,9-12H2,1H3/t16-/m0/s1
InChi Key
FEEUIAMWBWZZNX-INIZCTEOSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 2 years
| SKU | CAYM-39117-10 |
|---|---|
| Supplier Part Number | 39117-10 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | Y |
| CAS Number | 3006795-68-9 |
| Energy Star | No |
| Green | No |
| Controlled | N |