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Cayman Tetrahydrocannabivarin Acetate (exempt preparation)
List Price
$312.00
Your Price
$312.00
Cayman Tetrahydrocannabivarin Acetate (exempt preparation) - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-39444-1
MFG.PART:
39444-1
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Flufenamic acid-d4 is intended for use as an internal standard for the quantification of flufenamic acid (Item No. ) by GC- or LC-MS. Flufenamic acid is a non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor (IC50s = 3 and 9.3 µM for human COX-1 and COX-2, respectively). Flufenamic acid inhibits TNF-α-induced increases in COX-2 levels and NF-κB activation in HT-29 colon cancer cells in a concentration-dependent manner. It inhibits calcium influx induced by fMLP (fMLF; Item No. ) or A23187 (Item No. ) in human polymorphonuclear leukocytes (PMN) with IC50 values of 29 and 14 µM, respectively. Flufenamic acid also activates various ion channels, including transient receptor potential canonical 6 (TRPC6) and the large-conductance calcium-activated potassium channel (KCa1.1). It also inhibits various ion channels, including TRPC3 and the cystic fibrosis transmembrane conductance regulator (CFTR). Flufenamic acid (20 mg/kg) reduces increases in intestinal fluid secretion and intestinal barrier disruption in mice infected with the El Tor variant of V. cholerae.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
2-[[3-(tri
CAS Number
1185071-99-1
Synonyms
- FFA-d4
- Fluphenamic Acid-d4
Molecular Formula
C14H6D4F3NO2
Formula Weight
285.3
Purity
≥99% deuterated forms (d1-d4)
Formulation
A solid
Solubility
- DMF: soluble
- DMSO: soluble
- Methanol: soluble
SMILES
OC(C(C([2H])=C([2H])C([2H])=C1[2H])=C1NC2=CC(C(F)(F)F)=CC=C2)=OOC(C(C([2H])=C([2H])C([2H])=C1[2H])=C1NC2=CC(C(F)(F)F)=CC=C2)=O
InChi Code
InChI=1S/C14H10F3NO2/c15-14(16,17)9-4-3-5-10(8-9)18-12-7-2-1-6-11(12)13(19)20/h1-8,18H,(H,19,20)/i1D,2D,6D,7D
InChi Key
LPEPZBJOKDYZAD-ZEJCXXMWSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-39444-1 |
|---|---|
| Featured | No |
| Supplier Part Number | 39444-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | Y |
| CAS Number | 885123-57-9 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |