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Cayman NPD-2975
List Price $294.00 Your Price $294.00
Cayman NPD-2975 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-39466-5
MFG.PART: 39466-5
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
NPD-2975 is an antiparasitic agent.1 It reduces the proliferation of T. brucei (IC50 = 63.1 nM) but not T. cruzi, L. infantum, P. falciparum, or human MRC-5 fibroblasts (IC50s = >6,000 nM for all). In vivo, NPD-2975 (50 mg/kg twice per day) reduces peripheral blood parasite levels below detection limits and increases survival in a mouse model of T. brucei infection.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
5-(4-fluorophenyl)-3-isopropyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one
Molecular Formula
C14H13FN4O
Formula Weight
272.3
Purity
≥98%
Formulation(Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
- DMSO: Soluble
- Methanol: Soluble
λmax
230, 292 nm
SMILES
FC1=CC=C(C2=NC(C(C(C)C)=NN3)=C3C(N2)=O)C=C1
InChi Code
InChI=1S/C14H13FN4O/c1-7(2)10-11-12(19-18-10)14(20)17-13(16-11)8-3-5-9(15)6-4-8/h3-7H,1-2H3,(H,18,19)(H,16,17,20)
InChi Key
OJEVXJSJYBCDSR-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 2 years
| SKU | CAYM-39466-5 |
|---|---|
| Supplier Part Number | 39466-5 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 3032452-65-3 |
| Energy Star | No |
| Green | No |
| Controlled | N |