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Cayman ST1936


Product Description
ST1936 is an agonist of the serotonin (5-HT) receptor subtype 5-HT6.1,2 It selectively binds to 5-HT6 (Ki = 31 nM) over 5-HT1A, 5-HT1B, 5-HT1D, 5-HT2A, 5-HT2B, 5-HT2C, 5-HT3, 5-HT4, 5-HT5A, and the serotonin transporter (SERT; Kis = >1,000 nM for all) but also binds to the 5-HT7 receptor (Ki = 168 nM).1 ST1936 induces cAMP accumulation in BHK fibroblasts (EC50 = 16 nM).2 It decreases the basal firing rate of dopaminergic neurons in the ventral tegmental area but not substantia nigra pars compacta in rats in a dose-dependent manner.3 ST1936 (10 and 30 mg/kg) prevents stress-induced decreases in vanilla sugar-sustained appetitive behavior, indicating anti-anhedonic-like activity, in rats.4 It induces self-administration in rats when administered at a dose of 1 mg/kg.5
WARNING This product is not for human or veterinary use.
Technical Information
- Acetonitrile: Soluble
Shipping & Storage Information
| SKU | CAYM-39811-10 |
|---|---|
| Supplier Part Number | 39811-10 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 1210-81-7 |
| Energy Star | No |
| Green | No |
| Controlled | N |

