Miltenyi Biotec Peptide Pool For Efficient Stimulation of Antigen-Specific Cd4+ and Cd8+ T Cells; 6 nmol/peptide

Miltenyi Biotec Stimulate T cells reactive to the spike protein of the SARS-CoV-2 Wuhan wild-type using PepTivator Peptide Pools. PepTivators are pools of lyophilized peptides, consisting mainly of 15-mer sequences with 11 amino acids overlap. PepTivator SARS-CoV-2 Prot_S Complete is a pool of lyophilized peptides, covering the complete protein coding sequence (aa 5–1273) of the surface or spike glycoprotein ("S") of SARS Coronavirus 2 (GenBank MN908947.3, Protein QHD43416.1). | The PepTivator is available in two different quality grades. The research-grade product has an average purity of 70%, whereas peptides of the premium-grade product are individually purified via HPLC having each a purity of >90%. | In contrast, other PepTivators covering the SARS-CoV-2 spike glycoprotein ("S") are available only in research grade quality. PepTivator SARS-CoV-2 Prot_S covers selected immunodominant sequence domains of the spike protein (aa 304–338, 421–475, 492–519, 683–707, 741–770, 785–802, and 885–1273), Prot_S1 the complete N-terminal S1 domain (aa 1–692) and Prot_S+ parts of the C-terminal S2 domain (aa 689–895). | In vitro stimulation of antigen-specific T cells with PepTivator Peptide Pools causes the secretion of effector cytokines and the up-regulation of activation markers, which then allow the detection and isolation of antigen-specific T cells. | | - MLTY (Additional S&H or Hazmat Fees May Apply)