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Sigma-Aldrich Bacitracin From Bacillus L
List Price $439.64 Your Price $439.64
Sigma-Aldrich Bacitracin From Bacillus Licheniformis Activity: > 60000 U/g (Potency) - SIAL (Additional S&H Or Hazmat Fees May Apply)
NETA PART: SIAL-11702-25G
MFG.PART: 11702-25G
UNSPSC: 12352200
Manufacturer: Sigma-Aldrich
biological source
Bacillus licheniformis
Quality Level
200
form
powder
specific activity
≥65 IU/mg
color
white to pale buff
antibiotic activity spectrum
Gram-positive bacteria
mode of action
cell wall synthesis | interferes
storage temp.
2-8°C
SMILES string
[H]N1[C@@H](Cc2cnc[nH]2)C(=O)N[C@H](CC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)NCCCC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)C3CSC(=N3)C(N)C(C)CC)[C@@H](C)CC)C(=O)N[C@H](CCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@H](Cc4ccccc4)C1=O
InChI
1S/C66H103N17O16S/c1-9-35(6)52(69)66-81-48(32-100-66)63(97)76-43(26-34(4)5)59(93)74-42(22-23-50(85)86)58(92)83-53(36(7)10-2)64(98)75-40-20-15-16-25-71-55(89)46(29-49(68)84)78-62(96)47(30-51(87)88)79-61(95)45(28-39-31-70-33-72-39)77-60(94)44(27-38-18-13-12-14-19-38)80-65(99)54(37(8)11-3)82-57(91)41(21-17-24-67)73-56(40)90/h12-14,18-19,31,33-37,40-48,52-54H,9-11,15-17,20-30,32,67,69H2,1-8H3,(H2,68,84)(H,70,72)(H,71,89)(H,73,90)(H,74,93)(H,75,98)(H,76,97)(H,77,94)(H,78,96)(H,79,95)(H,80,99)(H,82,91)(H,83,92)(H,85,86)(H,87,88)/t35?,36-,37-,40-,41+,42+,43-,44+,45-,46-,47+,48?,52?,53-,54-/m0/s1
Related Categories
Antibiotics
General description
Chemical structure: peptide
Application
Bacitracin is used to study disruption of bacterial cell wall synthesis at the level of peptidoglycan biosynthesis and isoprenyl metabolism. It is also used to study the biosynthesis of sterols and squalene.
Bacitracin has been used:
Bacitracin has been used:
- as a protease inhibitor[1]
- as a control antibiotic[2]
- for the calibration in size exclusion chromatography[3]
Biochem/physiol Actions
Bacitracin has been shown to decrease vancomycin-resistant Enterococcus faecium population in intestine.[4]
Bacitracin is a peptide antibiotic.
Antimicrobial spectrum: Gram-positive bacteria.
Mode of Action: Inhibits bacterial cell wall synthesis by inhibiting dephosphorylation of lipid pyrophosphate.
Antimicrobial spectrum: Gram-positive bacteria.
Mode of Action: Inhibits bacterial cell wall synthesis by inhibiting dephosphorylation of lipid pyrophosphate.
Packaging
5G, 25 g
Other Notes
Keep container tightly closed in a dry and well-ventilated place. Moisture sensitive. Keep in a dry place.
wgk_germany
WGK 2
PPE
Eyeshields, Gloves, type N95 (US)
| SKU | SIAL-11702-25G |
|---|---|
| Supplier Part Number | 11702-25G |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Sigma-Aldrich |
| Temperature | 2-8C |
| Refrigerated-Frozen | Y |
| ProductLine | SIAL |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 10.000000 |
| Lead Time | 9 |
| Hazardous | N |
| CAS Number | 1405-87-4 |
| Energy Star | No |
| Green | No |
| Controlled | N |