Sigma-Aldrich Cx546 - SIAL (Additional S

Assay

≥98% (TLC)

Quality Level

100

Form

solid

Manufacturer/Tradename

Calbiochem^®

Storage Condition

OK to freeze
protect from light

Color

off-white

Solubility

DMSO: soluble

Storage Temp.

2-8°C

Inchi

1S/C14H17NO3/c16-14(15-6-2-1-3-7-15)11-4-5-12-13(10-11)18-9-8-17-12/h4-5,10H,1-3,6-9H2

Inchi Key

LJUNPHMOGNFFOS-UHFFFAOYSA-N

General Description

A positive allosteric modulator selective for the AMPA receptors. Used in studies related to Schizophrenia, neuroplasticity, Autism and neuronal differentiation.

Biochem/Physiol Actions

Primary Target
AMPA

Warning

Toxicity: Standard Handling (A)

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Silverman, L., et Al. 2013.Neuropharmacol. 64,268.
Peleg-Raibstein, D., et Al. 2012.Curr. Antipsych. 2012,361.

Schitine, C., et Al. 2012.Eur. J. Neurosci. 35,1672.
Lipina, T., et Al. 2006.Neuropsychopharmacology. 32,745.
Arai, C., et Al. 2004.Neurosci. 123,1011.
Nagarajan, N., et Al. 2001.Neuropharmacol. 41,650.CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany