Sigma-Aldrich Insolution Srt1720 HCl

Quality Level

100

Assay

≥98% (HPLC)

Form

liquid

Manufacturer/Tradename

Calbiochem^®

Storage Condition

OK to freeze
avoid repeated freeze/thaw cycles
desiccated (hygroscopic)
protect from light

Storage Temp.

−70°C

Inchi

1S/C25H23N7OS.ClH/c33-24(22-13-27-20-7-3-4-8-21(20)28-22)29-19-6-2-1-5-18(19)23-15-32-17(16-34-25(32)30-23)14-31-11-9-26-10-12-31;/h1-8,13,15-16,26H,9-12,14H2,(H,29,33);1H

Inchi Key

DTGRRMPPXCRRIM-UHFFFAOYSA-N

General Description

An enhanced aqueous soluble version of SRT1720 (Cat. No. 567860).An enhanced aqueous soluble version of SRT1720 (Cat. No. 567860).

Please note that the molecular weight for this compound is batch-specific due to variable water content.

Biochem/Physiol Actions

Cell permeable: yesPrimary Target
SIRT3Reversible: yesSecondary Target
p300 HAT

Packaging

Packaged under inert gas

Warning

Toxicity: Standard Handling (A)

Physical Form

A 25 mm (10 mg/650 µl) sterile-filtered solution of SRT1720, HCl (Cat. No. 567860) in DMSO.

Reconstitution

Following initial thaw, aliquot and freeze (-20°C). Aliquots are stable for up to 6 months at -20°C.

Other Notes

Baur, J.A., et Al. 2012.Nat. Rev. Drug Discov. 11,443.
Minor, R.K., et Al. 2011.Sci. Rep. 1,70.

Huber, J.L., et Al. 2010.Future Med. Chem. 2,1751.
Pacholec, M., et Al. 2010.J. Biol. Chem. 285,8340.
Jin, L., et Al. 2009.Protein Sci. 18,514.
Feige, J.N., et Al. 2008.Cell Metab. 8,347.
Milne, J.C., et Al. 2007.Nature 450,712.CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany